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Springer Protocols eBook Series

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  • Exon Skipping and Inclusion Therapies

    Methods and Protocols

    Edited by Yusuke Echigoya, Rika Maruyama, Toshifumi Yokota ...
    Series series Springer Protocols
    This fully updated edition presents a collection of protocols reflecting the latest advancements in exon skipping and inclusion strategies. The book explores the design of antisense oligonucleotide therapies, in vitro and in vivo evaluation of exon skipping in Duchenne muscular dystrophy, enhancing exon skipping efficiency, as well as methods involving spinal muscular atrophy and other diseases. ... Read more

    $170.09 USD

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  • RNA Interference (RNAi)

    by Wiley ...
    Series series Life Science Research Fundamentals
    The 2006 Nobel Prize in Physiology or Medicine was awarded to Andrew Z. Fire and Craig C. Mello for their discovery of RNA interference (RNAi). RNAi is a biological process in which RNA molecules can silence (inhibit) or up- or down-regulate gene expression, typically by causing the destruction of specific messenger RNA (mRNA) molecules. This collection of articles begins with an introduction to ... Read more

    $27.99 USD

  • Antibiotics

    Targets, Mechanisms and Resistance

    Edited by Claudio O. Gualerzi, Letizia Brandi, Attilio Fabbretti, Cynthia L. Pon ...
    Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed.Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic ... Read more

    $169.00 USD

  • Translational Medicine

    Molecular Pharmacology and Drug Discovery

    Edited by Robert A. Meyers ...
    Series series Advances in Molecular Biology and Medicine
    This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of ... Read more

    $382.00 USD

  • Handbook of Glycomics

    Edited by Richard D. Cummings, J. Michael Pierce ...
    The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model ... Read more

    $90.99 USD

  • Drug Discovery Stories, Volume 2

    Edited by Bin Yu, Peng Zhan ...
    Drug Discovery Stories, Volume Two showcases the discovery journeys of recent blockbuster drugs approved between 2023 and 2024, along with promising drug candidates. This book delves into structural biology, biological functions of targets, hit compound identification, hit-to-lead optimization, binding modes, key biological and pharmacokinetic data, and clinical results. It also covers other ... Read more

    $179.99 USD

  • Chemistry and Pharmacology of Drug Discovery

    Edited by Jie Jack Li ...
    Case studies of 20 successful FDA-approved drugs, from biological rationale to clinical efficacy studies and state-of-the-art applicationsChemistry and Pharmacology of Drug Discovery illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines, discussing a total of 20 drugs that are all FDA-approved post 2021—some of which are first ... Read more

    $161.00 USD

  • Protein Therapeutics

    by Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, ... Read more

    $282.00 USD

  • Principles and Applications of Molecular Diagnostics

    Edited by A. Rita Horvath, Carl T. Wittwer, Jason Park, Nader Rifai ...
    Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor ... Read more

    $107.99 USD

  • Autophagy in Disease and Clinical Applications, Part C

    Edited by Daniel Klionsky ...
    Series Book 453 - Methods in Enzymology
    The third and final installment of Daniel J. Klionsky's new three-volume treatment of autophagy, this volume focuses on monitoring autophagy with regard to disease connections, and presents methods that can be used to analyze autophagy in clinical samples. Edited by one of the leading authorities in the field, this volume and its companion volumes, Autophagy: Lower Eukaryotes and Autophagy in ... Read more

    $173.99 USD

  • Bispecific Antibodies

    Methods and Protocols

    Edited by Masahiro Yasunaga ...
    Series series Springer Protocols
    This volume explores protocols and perspectives for the design, production, characterization, functional evaluation, and clinical translation of bispecific antibodies (BsAbs). Beginning with a variety of platforms for generating BsAbs, the book continues with sections covering protocols to evaluate T-cell-dependent bispecific antibodies, modeling and simulation approaches to support clinical ... Read more

    $179.99 USD

  • Advances in Clinical Chemistry

    by Gregory S. Makowski ...
    Series Book 128 - Advances in Clinical Chemistry
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the latest information on Clinical Chemistry - Offers outstanding and original reviews on a range of Clinical Chemistry research topics - Serves as an indispensable reference for researchers and ... Read more

    $184.99 USD