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“yvonne will”

1 - 12 de 12 resultados para “yvonne will”
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  • Drug Discovery Toxicology

    From Target Assessment to Translational Biomarkers

    Edición de J. Eric McDuffie, Andrew J. Olaharski, Brandon D. Jeffy, Yvonne Will ...
    As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.• Guides researchers as to what drug safety experiments are both practical and useful• Covers a variety of key topics – safety lead optimization, in vitro-in vivo ... Leer más

    $181.00 USD

  • Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

    Edición de Yvonne Will, James A. Dykens ...
    Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.• Covers both basic science and applied technology / methods• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects• ... Leer más

    $334.00 USD

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  • Lysosomes

    Biology, Diseases, and Therapeutics

    Edición de Frederick R. Maxfield, James M. Willard, Shuyan Lu ...
    Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development.• Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug ... Leer más

    $162.00 USD

  • Cancer as a Metabolic Disease

    On the Origin, Management, and Prevention of Cancer

    de Thomas Seyfried ...
    The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that ... Leer más

    $133.00 USD

    Disponible también en: Audiolibro

    Disponible también en: Audiolibro

  • Protein Misfolding Diseases

    Current and Emerging Principles and Therapies

    Edición de Marina Ramirez-Alvarado, Jeffery W. Kelly, Christopher M. Dobson ...
    Series Libro 14 - Wiley Series in Protein and Peptide Science
    An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific ... Leer más

    $218.00 USD

  • Antibiotics

    Targets, Mechanisms and Resistance

    Edición de Claudio O. Gualerzi, Letizia Brandi, Attilio Fabbretti, Cynthia L. Pon ...
    Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed.Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic ... Leer más

    $169.00 USD

  • Cancer Stem Cells

    Edición de William L. Farrar, PhD ...
    A remarkable paradigm shift has occurred in recent years regarding the biological origins of cancer. The cancer stem cell hypothesis challenged the foundational notions of cancer, and the therapeutic implications have been profound. Compelling evidence indicates that errors in the development of a small subset of adult stem cells can lead to cancer. Only this small sub-population of cells has the ... Leer más

    $109.99 USD

  • Stem Cells

    From Biology to Therapy, 2 Volumes

    Edición de Robert A. Meyers ...
    Series series Advances in Molecular Biology and Medicine
    This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with ... Leer más

    $256.00 USD

  • Lentiviral Vectors and Gene Therapy

    de David Escors, Karine Breckpot, Frederick Arce, Grazyna Kochan, Holly Stephenson ...
    Series series Biomedical and Life Sciences (R0)
    Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was ... Leer más

    $49.99 USD

  • Mitochondria and Cancer

    Edición de Keshav Singh, Leslie Costello ...
    Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration ... Leer más

    $134.99 USD

  • The AH Receptor in Biology and Toxicology

    de Raimo Pohjanvirta ...
    This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this ... Leer más

    $158.00 USD

  • Sarcopenia – Age-Related Muscle Wasting and Weakness

    Mechanisms and Treatments

    Edición de Gordon S. Lynch ...
    Series series Biomedical and Life Sciences (R0)
    Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the ... Leer más

    $188.99 USD