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  • Protein Formulation and Delivery

    Series series Drugs and the Pharmaceutical Sciences
    This title is intended to assist pharmaceutical scientists in the development of stable protein formulations during the early stages of the product development process, providing a comprehensive review of mechanisms and causes of protein instability in formulation development, coverage of accelerated stability testing methods and relevant analytica ... Leer más

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  • Pharmacology

    Principles and Practice

    Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant ... Leer más

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  • Proteomic and Metabolomic Approaches to Biomarker Discovery

    Edición de Haleem J. Issaq ...
    Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. ... Leer más

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  • Drug-like Properties: Concepts, Structure Design and Methods

    from ADME to Toxicity Optimization

    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug ... Leer más

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  • Drug-Like Properties

    Concepts, Structure Design and Methods from ADME to Toxicity Optimization

    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and ... Leer más

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  • Oral Controlled Release Formulation Design and Drug Delivery

    Theory to Practice

    Edición de Hong Wen, Kinam Park ...
    This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues. ... Leer más

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  • Aggregation of Therapeutic Proteins

    Edición de Wei Wang, Christopher J. Roberts ...
    This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has ... Leer más

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  • ADMET for Medicinal Chemists

    A Practical Guide

    Edición de Katya Tsaioun, Steven A. Kates ...
    This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the ... Leer más

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  • Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry

    Series Libro 1 - Handbook of Polymers for Pharmaceutical Technologies
    Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique ... Leer más

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  • Handbook of Biochemistry and Molecular Biology

    Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the Handbook of Biochemistry and Molecular Biology gathers a wealth of information not easily obtained, including information not found on the web.Presented in an organized, concise, and simple-to-use format, this popular reference allows ... Leer más

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  • Capillary Electrophoresis of Carbohydrates

    From Monosaccharides to Complex Polysaccharides

    Edición de Nicola Volpi ...
    Simple carbohydrates, complex oligosaccharides and polysaccharides all belong to a class of ubiquitous (macro)molecules that exhibit a wide range of biological functions, and the recent advent of enhanced enzymatic, chemical and analytical tools used to study these sugars has inaugurated a genuine explosion in the field of glycomics. Specifically, it has led to a deeper understanding of how ... Leer más

    $98.99 USD

  • A Practical Guide to Protein and Peptide Purification for Microsequencing

    Edición de Paul T. Matsudaira ...
    Why a Second Edition?The Second Edition provides practical answers to the general question, "How can I obtain useful sequence information from my protein or peptide?" rather than the more specific question asked in the first edition, "How can I obtain the N-terminal sequence?" Important new methods include ways of dealing with blocked N termini, computer analysis of protein sequences, and the ... Leer más

    $65.99 USD