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1 - 12 de 12 resultados para “jane nikles”
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  • The Essential Guide to N-of-1 Trials in Health

    Edición de Jane Nikles, Geoffrey Mitchell ...
    Series series Biomedical and Life Sciences (R0)
    N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced.Whether you ... Leer más

    $152.99 USD

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  • Decision Making in a World of Comparative Effectiveness Research

    A Practical Guide

    Edición de Howard G. Birnbaum, Paul E. Greenberg ...
    Series series Medicine (R0)
    In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings. While most of this burgeoning literature has focused on research findings, data and methods, Howard Birnbaum and Paul Greenberg (both of Analysis Group) have ... Leer más

    $89.99 USD

  • Antibiotics

    The Perfect Storm

    de David M. Shlaes ...
    Series series Biomedical and Life Sciences (R0)
    Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment ... Leer más

    $89.99 USD

  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    de Max Kuhn, Ian Peers, Stan Altan ...
    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Leer más

    $170.99 USD

  • Clinical Data Analysis on a Pocket Calculator

    Understanding the Scientific Methods of Statistical Reasoning and Hypothesis Testing

    de Ton J. Cleophas, Aeilko H. Zwinderman ...
    Series series Biomedical and Life Sciences (R0)
    In medical and health care the scientific method is little used, and statistical software programs are experienced as black box programs producing lots of p-values, but little answers to scientific questions. The pocket calculator analyses appears to be, particularly, appreciated, because they enable medical and health professionals and students for the first time to understand the scientific ... Leer más

    $80.99 USD

  • Intelligent Data Analysis in Medicine and Pharmacology

    Edición de Nada Lavrač, Elpida Keravnou-Papailiou, Blaz Zupan ...
    Series Libro 414 - The Springer International Series in Engineering and Computer Science
    Intelligent data analysis, data mining and knowledge discovery in databases have recently gained the attention of a large number of researchers and practitioners. This is witnessed by the rapidly increasing number of submissions and participants at related conferences and workshops, by the emergence of new journals in this area (e.g., Data Mining and Knowledge Discovery, Intelligent Data Analysis, ... Leer más

    $188.99 USD

  • Quantitative Decisions in Drug Development

    de Christy Chuang-Stein, Simon Kirby ...
    Series series Mathematics and Statistics (R0)
    This book offers a high-level treatise of evidence-based decisions in drug development. Because of the inseparable relationship between designs and decisions, a good portion of this book is devoted to the design of clinical trials. The book begins with an overview of product development and regulatory approval pathways. It then discusses how to incorporate prior knowledge into study design and ... Leer más

    $62.99 USD

  • Biostatistics and Microbiology: A Survival Manual

    de Daryl S. Paulson ...
    Series series Biomedical and Life Sciences (R0)
    influence on the conclusions that result. A very “conservative” statistic requires very strong proof to demonstrate significant differences, whereas a “liberal” one requires less. “Yuck,” you say already, “I just want to know the answer. ” To this, I respond, when in doubt, use a conventional statistical method, one that can be agreed on and accepted by most authorities. These conventional kinds ... Leer más

    $49.99 USD

  • Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

    de Joel S. Owen, Jill Fiedler-Kelly ...
    This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects• Provides examples of nonlinear modeling ... Leer más

    $102.00 USD

  • Cluster Randomised Trials

    de Richard J. Hayes, Lawrence H. Moulton ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the ... Leer más

    $73.99 USD

  • Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

    de Gernot Wassmer, Werner Brannath ...
    Series series Mathematics and Statistics (R0)
    This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven ... Leer más

    $134.99 USD

  • Heparin - A Century of Progress

    Edición de Clive P. Page, Rebecca Lever, Barbara Mulloy ...
    Series series Biomedical and Life Sciences (R0)
    Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the ... Leer más

    $287.99 USD