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  • Mitochondria in Liver Disease

    Edición de Derick Han, Neil Kaplowitz ...
    " excellent, well-organized, and timely."-Lester Packer and Enrique Cardenas, University of Southern California, Los Angeles, from the Series PrefaceThe liver is a vital organ that is responsible for a wide range of functions, most of which are essential for survival. The multitude of functions the liver performs makes it vulnerable to a wide range ... Leer más

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  • DNA Repair in Cancer Therapy

    Molecular Targets and Clinical Applications

    Edición de Mark R. Kelley ...
    Cancer therapeutics include an ever-increasing array of tools at the disposal of clinicians in their treatment of this disease. However, cancer is a tough opponent in this battle, and current treatments, which typically include radiotherapy, chemotherapy and surgery, are not often enough to rid the patient of his or her cancer. Cancer cells can become resistant to the treatments directed at them, ... Leer más

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  • Medicinal Chemistry of Anticancer Drugs

    Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research ... Leer más

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  • Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

    Edición de Yvonne Will, James A. Dykens ...
    Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.• Covers both basic science and applied technology / methods• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects• ... Leer más

    $334.00 USD

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Edición de M. A. Hayat ...
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series ... Leer más

    $179.99 USD

  • RNA Interference

    Application to Drug Discovery and Challenges to Pharmaceutical Development

    Edición de Paul H. Johnson ...
    RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA ... Leer más

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  • Mitochondria and Cancer

    Edición de Keshav Singh, Leslie Costello ...
    Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration ... Leer más

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  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 12

    Edición de M. A. Hayat ...
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating 'toxic assets' and promoting cell viability, hence, it has emerged as a new and potent modulator of ... Leer más

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  • Regulation of Carbohydrate Metabolism(1985)

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    de Beitner ...
    First Published in 1985. A collaboration of the latest research on regulation of carbohydrate metabolism. ... Leer más

    $225.99 USD

  • The AH Receptor in Biology and Toxicology

    This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this ... Leer más

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  • Cytochrome P450

    Structure, Mechanism, and Biochemistry

    Edición de Paul R. Ortiz de Montellano ...
    Series series Medicine (R0)
    This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the ... Leer más

    $395.99 USD

  • Molecular, Cellular, and Metabolic Fundamentals of Human Aging

    Molecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, ... Leer más

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