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  • Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics

    Edición de Danuta Herzyk, Lisa M. Plitnick ...
    Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, biosimilars, vaccines, cell and gene therapies and blood products. This book compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current ... Leer más

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  • Histopathology of Preclinical Toxicity Studies

    Interpretation and Relevance in Drug Safety Evaluation

    de Peter Greaves ...
    This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature ... Leer más

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  • In Vitro Methods in Pharmaceutical Research

    In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time ... Leer más

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  • Guidebook on Molecular Modeling in Drug Design

    Edición de N. Claude Cohen ...
    Specially designed computer software is revolutionizing procedures for structured or rational drug design and discovery. The Guidebook on Molecular Modeling in Drug Design serves as a manual for the analysis ofmolecular structure and the correlation of these structures with pharmacological reactions. Intended as an introductory guide for advanced students and professionals with an interest in ... Leer más

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  • Drug-Induced Liver Disease

    Edición de Neil Kaplowitz, Laurie D. DeLeve ...
    This field has shown tremendous growth in recent years, primarily due to the recognition that drug-induced liver disease is the most common cause of liver failure and one of the major contributors to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major ... Leer más

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  • USMLE Road Map Pharmacology, Second Edition

    Series series LANGE USMLE Road Maps
    USMLE Road Map: Pharmacology presents a concise and focused examination of the essential concepts in pharmacology. Through a streamlined and easy-to-follow hierarchical outline format, it guides students through the most important attributes of each drug class and reviews the mechanisms, actions, and side effects of each drug prototype. The outline is enhanced with an extensive and original ... Leer más

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  • Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill

    Series series Medicine (R0)
    This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics.Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the ... Leer más

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  • The New Drug Reimbursement Game

    A Regulator’s Guide to Playing and Winning

    Series series Medicine (R0)
    This comprehensive text presents a rigorous framework from within which regulators can respond strategically to the claim by the pharmaceutical industry that lower drug prices today lead to a loss for the population’s future health due to less innovation. It starts with a critical review of the empirical evidence of the return to consumers on their ongoing investment into high drug prices in order ... Leer más

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  • Drug Delivery

    Edición de Monika Schäfer-Korting ...
    Series series Biomedical and Life Sciences (R0)
    In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview ... Leer más

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  • Drug Delivery

    Engineering Principles for Drug Therapy

    Series series Topics in Chemical Engineering
    Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and ... Leer más

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  • Biophysical Characterization of Proteins in Developing Biopharmaceuticals

    Biophysical Characterization of Proteins in Developing Biopharmaceuticals is concerned with the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure this book takes the reader on a journey on how to best achieve this goal using the key relevant and practical methods commonly employed in the ... Leer más

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  • A Practical Handbook of Preparative HPLC

    This book is a distillation of twenty years of practical experience of the high pressure liquid chromatography (HPLC) process. Deliberately steering clear of complex theoretical aspects, this book concentrates on the everyday problems associated with the technique, making it perfect for frequent use in the laboratory and for those in the pharmaceutical, agrochemical and biotechnology industries ... Leer más

    $108.99 USD