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  • MicroRNA Detection and Pathological Functions

    Series series Chemistry and Material Science (R0)
    This book summarizes microRNA (miRNA) biology in a variety of pathological processes, emphasizing the significant potential applications of miRNA in diagnostics and prognostics, as well as novel drug targets. The conventional techniques used for miRNA detection including standard PCR, Northern blotting, microarray and clone methods are addressed. Recent emerging strategies in miRNA detection and ... Read more

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    Rapid advances in high-throughput genome sequencing technologies foreshadow a near-future in which millions of individuals will gain affordable access to their complete genome sequence. This promises to offer unprecedented insights into the fundamental biological nature of ourselves and our species: where we came from, how we begin our lives, how we develop and grow, how we interact with our ... Read more

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  • Finding the Genetic Cause and Therapy for Adhd, Autism and 22q

    A Journey Into Precision Medicine That Could Affect Millions Worldwide

    Discovery of genetic cause and drug therapy for ADHD, autism and 22q that will allow patients to control their symptoms for these three diseases is described. The discovery is by Hakon Hakonarson, MD, Ph.D. who, in 2015, found the genetic cause for the three diseases. He then conducted a clinical trial to prove that the drug NFC-1 could regulate and modulate the genetic mutation that caused the ... Read more

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  • Microwave/RF Applicators and Probes for Material Heating, Sensing, and Plasma Generation

    A Design Guide

    Interactions of electromagnetic fields with materials at high frequencies have given rise to a vast array of practical applications in industry, science, medicine, and consumer markets. Applicators or probes, which are the front end of these systems, provide the field that interacts with the material. This book takes an integrated approach to the area of high frequency applicators and probes for ... Read more

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  • Characterization of Protein Therapeutics using Mass Spectrometry

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    This book highlights current approaches and future trends in the use of mass spectrometry to characterize protein therapies. As one of the most frequently utilized analytical techniques in pharmaceutical research and development, mass spectrometry has been widely used in the characterization of protein therapeutics due to its analytical sensitivity, selectivity, and specificity. This book begins ... Read more

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  • Proteogenomics

    Edited by Ákos Végvári ...
    Series series Biomedical and Life Sciences (R0)
    This book highlights key technologies and identifies areas for further development in proteogenomics. The utility and usefulness of very large Omics data sets (Next Gen Sequencing of DNA, RNA-seq, ribosome profiling, mass spectrometry- and antibody-based proteomics) is discussed and opportunities and challenges of related bioinformatics applications are outlined.The reader will be able to ... Read more

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  • Molecular Beacons

    Series series Chemistry and Material Science (R0)
    Molecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications.This book is designed to bring ... Read more

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  • Next Generation Sequencing and Sequence Assembly

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    Series series Biomedical and Life Sciences (R0)
    The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about ... Read more

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  • Research on the Radiation Effects and Compact Model of SiGe HBT

    by Yabin Sun ...
    Series series Engineering (R0)
    This book primarily focuses on the radiation effects and compact model of silicon-germanium (SiGe) heterojunction bipolar transistors (HBTs). It introduces the small-signal equivalent circuit of SiGe HBTs including the distributed effects, and proposes a novel direct analytical extraction technique based on non-linear rational function fitting. It also presents the total dose effects irradiated by ... Read more

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  • Advanced Transmission Electron Microscopy

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    Series series Chemistry and Material Science (R0)
    This volume expands and updates the coverage in the authors' popular 1992 book, Electron Microdiffraction. As the title implies, the focus of the book has changed from electron microdiffraction and convergent beam electron diffraction to all forms of advanced transmission electron microscopy. Special attention is given to electron diffraction and imaging, including high-resolution TEM and STEM ... Read more

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  • Dynamics and Characterization of Composite Quantum Systems

    Series series Physics and Astronomy (R0)
    This thesis sheds new light on the fascinating properties of composite quantum systems.Quantum systems of different sizes, ranging from small bipartite systems to large many-body ensembles, can be studied with the help of modern quantum optical experiments. These experiments make it possible to observe a broad variety of striking features, including nonclassical correlations, complex dynamics and ... Read more

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