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  • Targeting Oncogenic Driver Mutations in Lung Cancer

    Series series Elements in Molecular Oncology
    The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncogenic drivers other than EGFR, their management and current advancements in treatment. It also ... Read more

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  • Cancer Immunotherapy Principles and Practice

    “Drs. Butterfield, Kaufman and Marincola on behalf of the SITC have created a comprehensive must-have resource covering the basic and translational science behind approved and investigational immune therapies, and disease-by-disease clinical application of the therapies, written by leaders in the field. The textbook will be highly valuable reading for those just entering the field and for ... Read more

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  • Targeted Therapy in Translational Cancer Research

    Series series Translational Oncology
    Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy ... Read more

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  • Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics

    Series series Medicine (R0)
    In the last decade, there has been a remarkable explosion of knowledge in hematologic cancer from basic molecular biology and pathology to clinical therapy. This has led to many new advance and insights in the understanding of pathobiology of malignant hematology. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack ... Read more

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  • New Drugs for Malignancy, An Issue of Hematology/Oncology Clinics of North America

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    Series Book Volume 26-3 - The Clinics: Internal Medicine
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  • Novel Developments in Stem Cell Mobilization

    Focus on CXCR4

    Series series Biomedical and Life Sciences (R0)
    Recently the CXCR4/CXCL12-axis has been recognized as one of the pivotal adhesion pathways by which hematopoietic stem cells are retained in the bone marrow. CXCR4 antagonists with different chemical specification are being developed. Pharmacology research guides the way to the rational development effective antagonists. One antagonist, plerixafor, is clinically approved now for stem cell ... Read more

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  • Metronomic Chemotherapy

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    Series series Biomedical and Life Sciences (R0)
    This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are ... Read more

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  • Cancer Immunotherapy Principles and Practice, Second Edition

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  • Combining Targeted Biological Agents with Radiotherapy

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    Series series Biomedical and Life Sciences (R0)
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    Series series Biomedical and Life Sciences (R0)
    This work will provide a historical perspective on tumor immunotherapy, discuss fundamental mechanisms of failed tumor rejection, look at passive strategies to boost anti-tumor immunity, as well as have an in-depth look at active strategies to boost anti-tumor immunity. ... Read more

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