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Showing 1 - 12 of 12 results for “john d haley”
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  • EGFR Signaling Networks in Cancer Therapy

    Edited by John D. Haley, William John Gullick ...
    Series series Cancer Drug Discovery and Development
    The epidermal gro wth factor (EGF ) receptor and its downstream signal transduction networks have been implicated in the ontology and maintenance of tumor tissues, which has motivated the discovery and development of molecularly targeted anti-EGF receptor therapies. Over decades of study, the EGF receptor structure, its ligand binding domains, the physical biochemistry underlying its intrinsic ... Read more

    $188.09 USD

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  • The Immunoassay Handbook

    Theory and Applications of Ligand Binding, ELISA and Related Techniques

    Edited by David Wild ...
    The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science ... Read more

    $194.39 USD

  • Handbook of Cell Signaling

    Edited by Ralph A. Bradshaw, Edward A. Dennis ...
    Series series Cell Biology
    Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular ... Read more

    $481.49 USD

  • Nitric Oxide

    Biology and Pathobiology

    Edited by Louis J. Ignarro ...
    Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide's role as a principal neurotransmitter moderating erectile function, a ... Read more

    $197.99 USD

  • Targeting Protein Kinases for Cancer Therapy

    by David J. Matthews, Mary E. Gerritsen ...
    An expert guide to targeting protein kinases in cancer therapyResearch has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication.Complete ... Read more

    $148.00 USD

  • miRNA Regulation of the Translational Machinery

    Edited by Robert E. Rhoads ...
    Series series Biomedical and Life Sciences (R0)

    $89.09 USD

  • Molecular Aspects of Hematologic Malignancies

    Diagnostic Tools and Clinical Applications

    Edited by Michal Witt, Malgorzata Dawidowska, Tomasz Szczepanski ...
    Series series Biomedical and Life Sciences (R0)
    This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid ... Read more

    $143.09 USD

  • Anticancer Drug Development

    Edited by Bruce C. Baguley, David J. Kerr ...
    Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and ... Read more

    $161.99 USD

  • Advances in Biology and Therapy of Multiple Myeloma

    Volume 1: Basic Science

    Edited by Nikhil C. Munshi, Kenneth C. Anderson ...
    Series series Biomedical and Life Sciences (R0)
    Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great promise to ... Read more

    $143.09 USD

  • The Treatment of Myeloid Malignancies with Kinase Inhibitors, An Issue of Hematology/Oncology Clinics of North America

    by Ann Mullally, MD ...
    Series Book Volume 31-4 - The Clinics: Internal Medicine
    This issue of Hematology/Oncology Clinics will focus on The Treatment of Myeloid Malignancies with Kinase Inhibitors. Articles will focus on: Targeting aberrant signaling in myeloid malignancies: promise versus reality; The development and use of imatinib for the treatment of chronic myelogenous leukemia; Mechanisms of resistance to ABL kinase inhibition in CML and the development of next ... Read more

    $83.69 USD

  • Cell Signaling & Molecular Targets in Cancer

    Edited by Malay Chatterjee, Khosrow Kashfi ...
    This book provides an overview of critical components of cell signaling machinery and its role in epithelial morphogenesis, proliferation, invasions and angiogenesis in human cancer and discusses novel types of protein kinase pathways. ... Read more

    $143.09 USD

  • Protein Tyrosine Phosphatase Control of Metabolism

    Edited by Kendra K. Bence ...
    Series series Biomedical and Life Sciences (R0)
    Although phosphorylation of proteins on tyrosine is relatively rare compared to phosphorylation on serine or threonine residues, the past two decades of research into PTP function have led to a great appreciation of the critical role PTPs have in regulating basic cellular processes. Among these important roles is the regulation of cellular signaling pathways related to metabolism. This volume ... Read more

    $143.09 USD