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  • Environmental Epigenomics in Health and Disease

    Epigenetics and Complex Diseases

    Series series Biomedical and Life Sciences (R0)
    There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the ... Read more

    $188.09 USD

  • Environmental Epigenomics in Health and Disease

    Epigenetics and Disease Origins

    Series series Biomedical and Life Sciences (R0)
    There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the ... Read more

    $188.09 USD

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    Development and Developmental Disorders of the Human Central Nervous System

    Series series Medicine (R0)
    This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischemic causes. The introductory chapters give an overview of the development of the human brain and the spinal cord, the mechanisms of development as obtained in experimental studies of various ... Read more

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  • Wilson’s Disease

    A Clinician’s Guide to Recognition, Diagnosis, and Management

    Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, and psychiatrists are the specialists who will most likely see some Wilson's disease patients during their careers. See them - yes. Recognize and diagnose them - maybe. If you are in one of these specialties, and a patient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, or mood disorder, is ... Read more

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  • Transcriptomics and Gene Regulation

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    Series series Biomedical and Life Sciences (R0)
    This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, ... Read more

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  • The Palgrave Handbook of Biology and Society

    Series series Social Sciences (R0)
    This comprehensive handbook synthesizes the often-fractured relationship between the study of biology and the study of society. Bringing together a compelling array of interdisciplinary contributions, the authors demonstrate how nuanced attention to both the biological and social sciences opens up novel perspectives upon some of the most significant sociological, anthropological, philosophical and ... Read more

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  • Phosphoinositides I: Enzymes of Synthesis and Degradation

    Series series Biomedical and Life Sciences (R0)
    Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial ... Read more

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  • Gene Therapy for Acute and Acquired Diseases

    Edited by Phillip H. Factor ...
    In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and cancers. However, current gene transfer technology is limited in its transduction efficiency and ability to permanently and safely correct genomic defects. Thus the promise of gene therapy for these conditions is as yet unrealized. The progression of ... Read more

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  • Neurodegenerative Diseases

    Clinical Aspects, Molecular Genetics and Biomarkers

    Series series Medicine (R0)
    This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of ... Read more

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  • Genetics and Society

    A Sociology of Disease

    by Anne Kerr ...
    Genetic science has advanced rapidly in recent years; things happen now that might have seemed like science fiction only ten years ago. Genetics and Society looks at the history of this science and the wide-ranging impact it has had on contemporary society. Using fascinating and cutting-edge examples throughout, Anne Kerr examines topics as diverse as:the institutional structures that have grown ... Read more

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  • Maternal Influences on Fetal Neurodevelopment

    Clinical and Research Aspects

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    Novel Approaches into the Origins of Neurodevelopmental Disorders: The Fetal Physiology Foundation Over the past two decades, autism, a neurodevelopmental disorder that is defined by behavior and was once believed to be rare, became recognized in increasing numbers of children and recently received distinction as an “epidemic” [1]. While numbers of affected children have steadily increased, our ... Read more

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