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  • FXTAS, FXPOI, and Other Premutation Disorders

    Series series Biomedical and Life Sciences (R0)
    This book should serve as a resource for professionals in all fields regarding diagnosis, management, and counseling of patients with FXTAS, FXPOI and their families, as well as presenting the molecular basis for disease that may lead to the identification of new markers to predict disease risk and eventually lead to target treatments.The book will present information on all aspects of FXTAS, ... Read more

    $98.99 USD

  • The Fragile X-Associated Tremor Ataxia Syndrome (FXTAS)

    Series series Biomedical and Life Sciences (R0)
    In Fragile X-Associated Tremor Ataxia Syndrome (FXTAS), the editors present information on all aspects of FXTAS, including clinical features and current supportive management, radiological, psychological, and pathological findings, genotype-phenotype relationships, animal models and basic molecular mechanisms. Genetic counseling issues are also discussed. The book should serve as a resource for ... Read more

    $134.99 USD

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    Series series Biomedical and Life Sciences (R0)
    Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial ... Read more

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  • Trinucleotide Diseases and Instability

    Edited by Ben A. Oostra ...
    Series series Biomedical and Life Sciences (R0)
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 ... Read more

    $49.99 USD

  • Estrogen — Mystery Drug for the Brain?

    The Neuroprotective Activities of the Female Sex Hormone

    It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to ... Read more

    $89.99 USD

  • Advances in Down Syndrome Research

    Edited by Gert Lubec ...
    Series series Medicine (R0)
    "Advances in Down Syndrome Research” represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell ... Read more

    $143.99 USD

  • Therapeutic Angiogenesis for Vascular Diseases

    Molecular Mechanisms and Targeted Clinical Approaches for the Treatment of Angiogenic Disease

    Edited by Mark Slevin ...
    Series series Biomedical and Life Sciences (R0)
    Angiogenesis is the growth of new blood vessels and is a key process which occurs during pathological disease progression. Excessive and damaging angiogenesis occurs in diseases such as cancer, diabetic retinopathies, age-related macular degeneration and atherosclerosis. In other diseases such as stroke and myocardial infarction, insufficient or improper angiogenesis results in tissue loss and ... Read more

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  • Mortalin Biology: Life, Stress and Death

    Edited by Sunil C. Kaul, Renu Wadhwa ...
    Series series Biomedical and Life Sciences (R0)
    The phrase “Life, stress and death” connects three terms, but is there a biological basis for that? Are there molecules that are essential to/or mediate these phenomena? This contributory volume “Mortalin Biology: Life, Stress and Death” is a remarkable compilation of the research outcomes on the stress protein mortalin, a member of heat shock 70 family of proteins. The book is unique as it ... Read more

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  • Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments

    Series series Biomedical and Life Sciences (R0)
    Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat ... Read more

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  • Arterial Chemoreceptors in Physiology and Pathophysiology

    Series series Biomedical and Life Sciences (R0)
    Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds ... Read more

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  • Behavioral Neurogenetics

    Edited by John F. Cryan, Andreas Reif ...
    Series series Biomedical and Life Sciences (R0)
    This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Indeed in juxtaposing both areas of research the reader will appreciate the true translational nature of the field. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, ... Read more

    $188.99 USD