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Showing 1 - 12 of 12 results for “daniel e johnson”
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  • Targeting Cell Survival Pathways to Enhance Response to Chemotherapy

    by Daniel E. Johnson, Benjamin Bonavida ...
    Series Book 3 - Cancer Sensitizing Agents for Chemotherapy
    Targeting Cell Survival Pathways to Enhance Response to Chemotherapy encompasses recently developed molecular targeting agents and approaches that suppress cell survival signaling. Cell survival signaling attenuates the effectiveness of conventional chemotherapy and numerous mechanisms have been described, and continue to be described, which contribute to cell survival in the face of chemotherapy ... Read more

    $157.49 USD

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  • Targeting Protein Kinases for Cancer Therapy

    by David J. Matthews, Mary E. Gerritsen ...
    An expert guide to targeting protein kinases in cancer therapyResearch has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication.Complete ... Read more

    $148.00 USD

  • Translational Endocrinology of Bone

    Reproduction, Metabolism, and the Central Nervous System

    Edited by Gerard Karsenty ...
    The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and ... Read more

    $124.19 USD

  • Pharmacogenomics of Human Drug Transporters

    Clinical Impacts

    by Toshihisa Ishikawa, Richard B. Kim, Jörg König ...
    Sets the foundation for safer, more effective drug therapiesWith this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse ... Read more

    $148.00 USD

  • Resistance of Cancer Cells to CTL-Mediated Immunotherapy

    Edited by Benjamin Bonavida, Salem Chouaib ...
    Series series Biomedical and Life Sciences (R0)
    This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, ... Read more

    $89.09 USD

  • Translational Cancer Research for Surgeons, An Issue of Surgical Oncology Clinics

    by William G. Cance, MD ...
    Series Book Volume 22-4 - The Clinics: Surgery
    This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. William G. Cance, is devoted to Translational Cancer Research for Surgeons. Translational Cancer research aims to move bench research to the bedside by applying basic science toward potential therapies. This issue will present the concepts of translational research and development of targeted therapeutics, and its ... Read more

    $75.59 USD

  • Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics

    Edited by Jianguo Tao, Eduardo Sotomayor ...
    Series series Medicine (R0)
    In the last decade, there has been a remarkable explosion of knowledge in hematologic cancer from basic molecular biology and pathology to clinical therapy. This has led to many new advance and insights in the understanding of pathobiology of malignant hematology. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack ... Read more

    $143.09 USD

  • Targeted Therapy in Translational Cancer Research

    by Maurie Markman, Ernest Hawk, Robert C. Bast Jr. ...
    Series series Translational Oncology
    Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy ... Read more

    $138.00 USD

  • Advances in Biology and Therapy of Multiple Myeloma

    Volume 1: Basic Science

    Edited by Nikhil C. Munshi, Kenneth C. Anderson ...
    Series series Biomedical and Life Sciences (R0)
    Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great promise to ... Read more

    $143.09 USD

  • New Drugs for Malignancy, An Issue of Hematology/Oncology Clinics of North America

    by Franco Muggia ...
    Series Book Volume 26-3 - The Clinics: Internal Medicine
    Topics include: Targeting IGF-1R, Tyrosine Kinase Inhibitors in Lung Cancer, Targeting mTOR, Targeting Hedgehog, Mitotic Inhibitors, Topoisomerase I Inhibitors , and New Strategies and Drugs Inhibiting Folate Pathways. ... Read more

    $75.59 USD

  • Glioblastoma:

    Molecular Mechanisms of Pathogenesis and Current Therapeutic Strategies

    Edited by Swapan K. Ray ...
    Series series Biomedical and Life Sciences (R0)
    Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is ... Read more

    $188.09 USD

  • Growth Hormone Related Diseases and Therapy

    A Molecular and Physiological Perspective for the Clinician

    Edited by Ken Ho ...
    Series series Medicine (R0)
    The molecular era ushered in the cloning of the growth hormone (GH) gene and the production of unlimited amounts of GH through recombinant technology. The continuing momentum of research from basic science to clinical evaluation has brought unprecedented advances to the understanding of GH biology for the clinical endocrinologist. Growth Hormone Related Diseases and Therapy: A Molecular and ... Read more

    $188.09 USD