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    Series series Elements in Molecular Oncology
    Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a clinically important driver alteration affecting approximately one-third of lung cancer patients. Treatments for EGFR-exon 19 deletion and exon 21 L858R NSCLC have evolved over the last decade from first-generation reversible tyrosine kinase inhibitors (TKI) to third-generation irreversible TKIs, of which ... Read more

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    Series series Emerging Cancer Therapeutics
    Emerging Cancer Therapeutics is a trinary hard cover periodical that is designed to provide an up-to-date evidence-based review of a dedicated emerging cancer therapy topic of interest to clinicians and scientists involved in the care of patients receiving cancer treatment. It will serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinical oncologists, ... Read more

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  • Targeting Protein Kinases for Cancer Therapy

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  • Metronomic Chemotherapy

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    Edited by Guido Bocci, Giulio Francia ...
    Series series Biomedical and Life Sciences (R0)
    This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are ... Read more

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  • Novel Developments in Stem Cell Mobilization

    Focus on CXCR4

    Series series Biomedical and Life Sciences (R0)
    Recently the CXCR4/CXCL12-axis has been recognized as one of the pivotal adhesion pathways by which hematopoietic stem cells are retained in the bone marrow. CXCR4 antagonists with different chemical specification are being developed. Pharmacology research guides the way to the rational development effective antagonists. One antagonist, plerixafor, is clinically approved now for stem cell ... Read more

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  • Hodgkin's Lymphoma, An Issue of Hematology/Oncology

    Hodgkin's Lymphoma, An Issue of Hematology/Oncology

    Series Book Volume 28-1 - The Clinics: Internal Medicine
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  • Combining Targeted Biological Agents with Radiotherapy

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  • New Drugs for Malignancy, An Issue of Hematology/Oncology Clinics of North America

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    Series Book Volume 26-3 - The Clinics: Internal Medicine
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  • The Treatment of Myeloid Malignancies with Kinase Inhibitors, An Issue of Hematology/Oncology Clinics of North America

    Series Book Volume 31-4 - The Clinics: Internal Medicine
    This issue of Hematology/Oncology Clinics will focus on The Treatment of Myeloid Malignancies with Kinase Inhibitors. Articles will focus on: Targeting aberrant signaling in myeloid malignancies: promise versus reality; The development and use of imatinib for the treatment of chronic myelogenous leukemia; Mechanisms of resistance to ABL kinase inhibition in CML and the development of next ... Read more

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    Series series Medicine (R0)
    In the last decade, there has been a remarkable explosion of knowledge in hematologic cancer from basic molecular biology and pathology to clinical therapy. This has led to many new advance and insights in the understanding of pathobiology of malignant hematology. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack ... Read more

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