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christopher p leamon

Showing 1 - 12 of 12 results for “christopher p leamon
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  • Targeted Drug Strategies for Cancer and Inflammation

    Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase inhibitor, methotrexate, and the thymidylate synthase inhibitors, raltitrexed and pemetrexed. Major advances in folate research made ... Read more

    $143.09 USD

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  • Miracle Medicines

    Seven Lifesaving Drugs and the People Who Created Them

    It’s the business of saving lives.Miracle Medicines goes behind the scenes of the pharmaceutical industry and into the high-security laboratories to tell the stories of the men and women---chemists, physiologists, medical and clinical researchers, engineers---who have chosen to toil for years in the lab in order to transform scientific theories into new lifesaving medicines.You’ll witness the day ... Read more

    $6.99 USD

  • Placebo Effects

    Understanding the mechanisms in health and disease

    The placebo effect is one of the most widely used and familiar terms within science and medicine, yet it is not always clear just what we mean by a placebo effect.Though we might describe a placebo effect as being 'all in the mind', we now know that there is a genuine neurobiological basis to this phenomenon. In recent years our knowledge of the neural bases of the placebo effect has developed ... Read more

    $53.99 USD

  • Casebook in Clinical Pharmacokinetics and Drug Dosing

    by Henry Cohen ...
    A STEP-BY-STEP APPROACH TO DESIGNING ACCURATE DOSING REGIMENSCasebook in Pharmacokinetics and Drug Dosing uses real-life cases to teach pharmacy students, pharmacists, and clinical pharmacists how to apply pharmacokinetics to formulate proper dosing regimens. In order to be as clinically relevant as possible, the book not only discusses drugs with readily available therapeutic serum levels, but ... Read more

    $44.09 USD

  • Drug-Like Properties

    Concepts, Structure Design and Methods from ADME to Toxicity Optimization

    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and ... Read more

    $179.99 USD

  • Fundamental Research in Ultra High Dilution and Homoeopathy

    Edited by J. Schulte, P.C. Endler ...
    Jurgen Schulte and Christian Endler met in 1990 at an international conference on the Structure of Water held in the Lecture Halls of the University of Graz (Austria). Disappointed by the lack of a systematic strategy of research into the physics of homoeopathy Jurgen Schulte started to work on the establishment of scientifically acceptable research standards in physics of homoeopathy and ... Read more

    $143.09 USD

  • Histopathology of Preclinical Toxicity Studies

    Interpretation and Relevance in Drug Safety Evaluation

    by Peter Greaves ...
    This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature ... Read more

    $175.49 USD

  • Biopharmaceuticals

    Biochemistry and Biotechnology

    by Gary Walsh ...
    The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology.This ... Read more

    $118.00 USD

  • Polypharmacology in Drug Discovery

    Edited by Jens-Uwe Peters ...
    An essential outline of the main facets of polypharmacology in drug discovery researchExtending drug discovery opportunities beyond the "one drug, one target" philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of ... Read more

    $127.00 USD

  • Mucosal Delivery of Biopharmaceuticals

    Biology, Challenges and Strategies

    Series series Biomedical and Life Sciences (R0)
    Biopharmaceutical medicines, the newest class of therapeutics, are quite heterogeneous and include a range of molecules such as proteins, peptides, vaccines and nucleic acids, with use in virtually all therapeutic fields (e.g. cancer and infectious diseases, vaccination, metabolic dysfunctions) and diagnostics. This edited book gives a concise and up-to-date overview of the biological features ... Read more

    $143.09 USD

  • Improving the Regulatory Review Process: Assessing Performance and Setting Targets

    Edited by N. McAuslane, S.R. Walker ...
    Series series Biomedical and Life Sciences (R0)
    At a time when it is becoming usual for medicines to be developed for a global market and pharmaceutical companies are endeavouring to expedite the drug development process, Regulatory Authorities are concentrating on improving their efficiency and effectiveness. Therefore, it is not surprising that questions are being asked as to how performance might be measured and compared between different ... Read more

    $49.49 USD

  • New Approaches to Drug Discovery

    Series Book 232 - Handbook of Experimental Pharmacology
    This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and ... Read more

    $188.09 USD