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Showing 1 - 12 of 12 results for “balazs halmos”
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  • Targeting Oncogenic Driver Mutations in Lung Cancer

    by Matthew Lee, Fawzi Abu Rous, Alain Borczuk, Stephen Liu, Shirish Gadgeel, Balazs Halmos ...
    Series series Elements in Molecular Oncology
    The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncogenic drivers other than EGFR, their management and current advancements in treatment. It also ... Read more

    $20.49 USD

  • EGFR-Directed Therapy in Lung Cancer

    by So Yeon Kim, Daniel B. Costa, Daisuke Shibahara, Susumu Kobayashi, Balazs Halmos ...
    Series series Elements in Molecular Oncology
    Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a clinically important driver alteration affecting approximately one-third of lung cancer patients. Treatments for EGFR-exon 19 deletion and exon 21 L858R NSCLC have evolved over the last decade from first-generation reversible tyrosine kinase inhibitors (TKI) to third-generation irreversible TKIs, of which ... Read more

    $20.49 USD

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  • Novel Developments in Stem Cell Mobilization

    Focus on CXCR4

    Edited by Stefan Fruehauf, Gary Calandra, W. Jens Zeller ...
    Series series Biomedical and Life Sciences (R0)
    Recently the CXCR4/CXCL12-axis has been recognized as one of the pivotal adhesion pathways by which hematopoietic stem cells are retained in the bone marrow. CXCR4 antagonists with different chemical specification are being developed. Pharmacology research guides the way to the rational development effective antagonists. One antagonist, plerixafor, is clinically approved now for stem cell ... Read more

    $143.09 USD

  • Metronomic Chemotherapy

    Pharmacology and Clinical Applications

    Edited by Guido Bocci, Giulio Francia ...
    Series series Biomedical and Life Sciences (R0)
    This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are ... Read more

    $89.09 USD

  • New Drugs for Malignancy, An Issue of Hematology/Oncology Clinics of North America

    by Franco Muggia ...
    Series Book Volume 26-3 - The Clinics: Internal Medicine
    Topics include: Targeting IGF-1R, Tyrosine Kinase Inhibitors in Lung Cancer, Targeting mTOR, Targeting Hedgehog, Mitotic Inhibitors, Topoisomerase I Inhibitors , and New Strategies and Drugs Inhibiting Folate Pathways. ... Read more

    $75.59 USD

  • Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics

    Edited by Jianguo Tao, Eduardo Sotomayor ...
    Series series Medicine (R0)
    In the last decade, there has been a remarkable explosion of knowledge in hematologic cancer from basic molecular biology and pathology to clinical therapy. This has led to many new advance and insights in the understanding of pathobiology of malignant hematology. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack ... Read more

    $143.09 USD

  • Targeted Therapy in Translational Cancer Research

    by Maurie Markman, Ernest Hawk, Robert C. Bast Jr. ...
    Series series Translational Oncology
    Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy ... Read more

    $138.00 USD

  • Combining Targeted Biological Agents with Radiotherapy

    Current Status and Future Directions

    by William Small Jr., MD ...
    Radiotherapy plays an integral role in cancer treatment. Approximately 60% of cancer patients will receive radiotherapy at some point in their treatment. A major improvement in patient outcomes occurs with the use of combined chemotherapy and radiotherapy. The combination of targeted biological agents with radiotherapy is the latest cutting-edge extension in cancer therapy for radiation ... Read more

    $161.99 USD

  • Renal Cell Carcinoma

    Translational Biology, Personalized Medicine, and Novel Therapeutic Targets

    Edited by Robert A. Figlin, W. Kimryn Rathmell, Brian I. Rini ...
    Series series Biomedical and Life Sciences (R0)
    This book provides a comprehensive look at renal cell carcinoma, exploring its biology as well as current and future molecular targets for renal cancer carcinoma. ... Read more

    $143.09 USD

  • Cancer Immunotherapy

    Paradigms, Practice and Promise

    Edited by Tyler J. Curiel ...
    Series series Biomedical and Life Sciences (R0)
    This work will provide a historical perspective on tumor immunotherapy, discuss fundamental mechanisms of failed tumor rejection, look at passive strategies to boost anti-tumor immunity, as well as have an in-depth look at active strategies to boost anti-tumor immunity. ... Read more

    $143.09 USD

  • Fusion Protein Technologies for Biopharmaceuticals

    Applications and Challenges

    Edited by Stefan R. Schmidt ...
    The state of the art in biopharmaceutical FUSION PROTEIN DESIGNFusion proteins belong to the most lucrative biotech drugs-with Enbrel® being one of the best-selling biologics worldwide. Enbrel® represents a milestone of modern therapies just as Humulin®, the first therapeutic recombinant protein for human use, approved by the FDA in 1982 and Orthoclone® the first monoclonal antibody reaching the ... Read more

    $191.00 USD

  • New Insights into Rheumatoid Arthritis, An Issue of Rheumatic Disease Clinics

    by David A. Fox, MD ...
    Series Book Volume 36-2 - The Clinics: Internal Medicine
    There are numerous monographs devoted to rheumatoid arthritis. What sets this issue apart is that it keeps an eye to the future. Topics explored include measurement of RA disease activity today and in the future; epidemiology of RA – implications for prevention and risk assessment; genes that predispose to RA – relevance to current and future therapeutic strategies; multiple kinases – assessment ... Read more

    $75.59 USD